Practical iron-catalyzed dehalogenation of aryl halides.
نویسندگان
چکیده
An operationally simple iron-catalyzed hydrodehalogenation of aryl halides has been developed with 1 mol% Fe(acac)(3) and commercial t-BuMgCl as reductant. The mild reaction conditions (THF, 0 degrees C, 1.5 h) effect rapid chemoselective dehalogenation of (hetero)aryl halides (I, Br, Cl) and tolerate F, Cl, OR, SR, CN, CO(2)R, and vinyl groups.
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ورودعنوان ژورنال:
- Chemical communications
دوره 46 34 شماره
صفحات -
تاریخ انتشار 2010